|The PRKDC prkdc (Catalog #MBS8243983) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The DNA-PKcs (pT2647) Blocking Peptide reacts with Human, Monkey and may cross-react with other species as described in the data sheet. MyBioSource\'s DNA-PKcs can be used in a range of immunoassay formats including, but not limited to, Blocking (BL).
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the PRKDC prkdc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PRKDC prkdc product has the following accession number(s) (GI #38258929) (NCBI Accession #P78527.3) (Uniprot Accession #P78527). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The peptide is used to block Anti-DNA-PKcs reactivity.
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry. PRKDC also interacts with the following gene(s): AKT1, DCLRE1C, H2AFX, LIG4, RPA2, TP53, UBC, XRCC4, XRCC5, XRCC6. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Prostate, Skin, Spleen tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Cell Transformation, Neoplastic, Chromosome Aberrations, Disease Models, Animal, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to DNA-PKcs (pT2647) Blocking Peptide.