|The PREX1 prex1 (Catalog #MBS543162) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PREX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western Blot: 1:500-1:750. Researchers should empirically determine the suitability of the PREX1 prex1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PREX1 prex1 product has the following accession number(s) (GI #148886999) (NCBI Accession #Q8TCU6.3) (Uniprot Accession #Q8TCU6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Western Blot Positive Control Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 1 protein
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3, 4, 5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Immunogen: Purified Protein
Expression: Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues. Molecular Function: enzyme binding, Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding
Subcellular Location: Cytoplasm, cell membrane. PREX1 also interacts with the following gene(s): MTOR, RAC1, RAC2, RAC3, RICTOR. Blood, Brain, Embryonic Tissue, Kidney, Lung, Lymph, Lymph Node, Nerve, Prostate, Vascular tissues are correlated with this protein. Breast Neoplasms, Disease Models, Animal, Glioblastoma, Inflammation, Kidney Diseases, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Skin Diseases are some of the diseases may be linked to PREX1 Positive Control.