PRDM6 blocking peptide product blog
Tags: Blocking Peptide; PRDM6; PRDM6 blocking peptide;
The PRDM6 prdm6 (Catalog #MBS9220765) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The PRDM6 prdm6 product has the following accession number(s) (GI #223590133) (NCBI Accession #Q9NQX0.2) (Uniprot Accession #Q9NQX0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates \'Lys-20\' of histone H4 in vitro. \'Lys-20\' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).
Cellular Location: Nucleus. Breast Neoplasms, Cardiovascular Abnormalities, Cardiovascular Diseases, Death, Heart Diseases, Hemorrhage, Hypertension, Nervous System Diseases are some of the diseases may be linked to PRDM6 Antibody (N-term) Blocking Peptide. Brain, Heart, Lung, Uncharacterized Tissue tissues are correlated with this protein.