PRDM14 blocking peptide product blog
Tags: Blocking Peptide; PRDM14; PRDM14 blocking peptide;
The PRDM14 prdm14 (Catalog #MBS9218883) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The PRDM14 prdm14 product has the following accession number(s) (GI #17368925) (NCBI Accession #Q9GZV8.1) (Uniprot Accession #Q9GZV8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5\'-GGTC[TC]CTAA-3\'.
Cellular Location: Nucleus. Tissue Location: Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level). The following patways have been known to be associated with this gene. Breast Neoplasms, Cell Transformation, Neoplastic, Fibrosis, Infertility, Male, Inflammation, Lung Neoplasms, Neoplasms, Experimental, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Respiratory Tract Diseases, Testicular Diseases are some of the diseases may be linked to PRDM14 Antibody (N-term) Blocking peptide. Embryonic Tissue, Testis tissues are correlated with this protein.