|The PPM1D ppm1d (Catalog #MBS9220265) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The PPM1D ppm1d product has the following accession number(s) (GI #10720176) (NCBI Accession #O15297.1) (Uniprot Accession #O15297). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates \'Ser-15\' of TP53 and \'Ser-345\' of CHEK1 which contributes to the functional inactivation of these proteins.
Blood, Bone, Brain, Liver, Lung, Lymph Node, Prostate, Spleen, Stomach, Vascular tissues are correlated with this protein. PPM1D also interacts with the following gene(s): ATM, CHEK1, CHEK2, H2AFX, HIPK2, JUN, MDM2, MDM4, RUNX2, TP53. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Chromosome Aberrations, Glioma, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Ovarian Neoplasms are some of the diseases may be linked to PPM1D Antibody (Center) Blocking peptide.