|The Ppif ppif (Catalog #MBS659743) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Cyclophilin D can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).
Suitable for use in ELISA. Researchers should empirically determine the suitability of the Ppif ppif for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Ppif ppif product has the following accession number(s) (GI #1549271) (NCBI Accession #AAB08453.1) (Uniprot Accession #P29117). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Cyclophilin D (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans isomeras, Cyclophilin-40, Cyclophilin-Related Protein, CYP40, CYP-40, CYPD, MGC33096, PPIase, Rotamase) (Control Peptide)
C-DENFHYKHDREG, from the internal region of human PPID.
Cyclophilin D (CyPD) is a member of the immunophilin family of proteins. Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents-cyclosporin A (CsA) or FK506. Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP\'s) and those which bind cyclosporin An are called cyclophilins (CyP). Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. As PPIase\'s, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins. CyPD is located in the inter-membrane space of the mitochondria where it has been shown to be an integral member of the permeability transition pore complex which also includes the voltage dependent anion channel (VDAC) and the adenine nucleotide translocator (ANT).
Positive Control: Human Brain (Frontal Cortex) lysates. Brain, Heart, Kidney, Liver, Pancreas, Prostate tissues are correlated with this protein. The following patways have been known to be associated with this gene. Ppif also interacts with the following gene(s): Dydc2, Sh2d4b. Cardiovascular Diseases, Disease Models, Animal, Drug-Induced Liver Injury, Edema, Fibrosis, Hypertrophy, Liver Diseases, Necrosis, Nervous System Diseases, Ulcer are some of the diseases may be linked to Cyclophilin D (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans isomeras, Cyclophilin-40, Cyclophilin-Related Protein, CYP40, CYP-40, CYPD, MGC33096, PPIase, Rotamase) (Control Peptide).