Pou5f1 blocking peptide product blog
Tags: POU5F1; Blocking Peptide; POU5F1 blocking peptide;
The Pou5f1 pou5f1 (Catalog #MBS9229945) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The Pou5f1 pou5f1 product has the following accession number(s) (GI #123403) (NCBI Accession #P20263.1) (Uniprot Accession #P20263). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Transcription factor that binds to the octamer motif (5\'-ATTTGCAT-3\'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Cellular Location: Cytoplasm. Nucleus. Note: Expressed in a diffuse and slightly punctuate pattern. Tissue Location: Expressed the totipotent and pluripotent stem cells of the pregastrulation embryo. Also expressed in primordial germ cells and in the female germ line. Absent from adult tissues. Pou5f1 also interacts with the following gene(s): Cdx2, Epas1, Esrrb, Foxd3, Klf4, Lin28a, Nanog, Sall4, Sox2, Zic3. The following patways have been known to be associated with this gene. Brain Diseases, Breast Neoplasms, Liver Diseases, Lung Diseases, Lung Neoplasms, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Experimental, Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms are some of the diseases may be linked to Pou5f1 Blocking Peptide (N-term). Embryonic Tissue, Eye, Ovary, Skin, Testis, Uncharacterized Tissue tissues are correlated with this protein.