PNPT1 blocking peptide product blog
Tags: Blocking Peptide; PNPT1; PNPT1 blocking peptide;
The PNPT1 pnpt1 (Catalog #MBS9222681) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The PNPT1 pnpt1 product has the following accession number(s) (GI #115502437) (NCBI Accession #Q8TCS8.2) (Uniprot Accession #Q8TCS8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3\'-to-5\' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3\' overhang double- stranded RNA with a 3\'-to-5\' directionality in an ATP-dependent manner. Required for correct processing and polyadenylation of mitochondrial mRNAs. Plays a role as a cytoplasmic RNA import factor that mediates the translocation of small RNA components, like the 5S RNA, the RNA subunit of ribonuclease P and the mitochondrial RNA-processing (MRP) RNA, into the mitochondrial matrix. Plays a role in mitochondrial morphogenesis and respiration; regulates the expression of the electron transport chain (ETC) components at the mRNA and protein levels. In the cytoplasm, shows a 3\'-to-5\' exoribonuclease mediating mRNA degradation activity; degrades c-myc mRNA upon treatment with IFNB1/IFN-beta, resulting in a growth arrest in melanoma cells. Regulates the stability of specific mature miRNAs in melanoma cells; specifically and selectively degrades miR-221, preferentially. Plays also a role in RNA cell surveillance by cleaning up oxidized RNAs. Binds to the RNA subunit of ribonuclease P, MRP RNA and miR-221 microRNA.
Cellular Location: Cytoplasm. Mitochondrion. Mitochondrion intermembrane space; Peripheral membrane protein. Diabetes Mellitus, Type 2, Inflammation, Neoplasm Invasiveness, Prostatic Neoplasms are some of the diseases may be linked to PNPT1 Antibody (Center) Blocking Peptide. Blood, Bone, Bone Marrow, Brain, Eye, Prostate, Skin, Stomach, Testis tissues are correlated with this protein. The following patways have been known to be associated with this gene.