|The PLGF 1 pgf (Catalog #MBS142295) is a Recombinant Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase.
The PLGF 1 pgf product has the following accession number(s) (GI #333033785) (NCBI Accession #NP_001193941.1) (Uniprot Accession #P49763). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Leu-Pr o-Ala-Val.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Placenta Growth Factor-1 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized Placenta Growth Factor 1 in sterile 0.1M acetic acid or PBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: The ED50 as determined by its ability to bind to immobilized rh-sFlt-1 in a functional ELISA. PlGF-1 human Recombinant can bind to immobilized rh-sFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml, corresponding to a Specific Activity of 1x105-2x106units/mg. Brain Diseases, Cardiovascular Diseases, Death, Disease Models, Animal, Heart Diseases, Hypertension, Inflammation, Kidney Diseases, Lung Diseases, Necrosis are some of the diseases may be linked to Recombinant Human Placenta Growth Factor-1. PLGF 1 also interacts with the following gene(s): AKT1, EDN1, FLT1, FLT4, KDR, NRP1, PIK3CA, VEGFA. The following patways have been known to be associated with this gene. Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Ovary, Placenta, Uterus tissues are correlated with this protein.