PLEKHG5 blocking peptide product blog
Tags: Blocking Peptide; PLEKHG5; PLEKHG5 blocking peptide;
The PLEKHG5 plekhg5 (Catalog #MBS9222443) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The PLEKHG5 plekhg5 product has the following accession number(s) (GI #160014162) (NCBI Accession #O94827.3) (Uniprot Accession #O94827). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
Cellular Location: Cytoplasm. Cytoplasm, perinuclear region. Cell junction Cell projection, lamellipodium. Note: Predominantly cytoplasmic, however when cells are stimulated found in perinuclear regions. Localized at cell-cell junctions in quiescent endothelial cells, it relocalizes to cytoplasmic vesicle and the leading edge of lamellipodia in migrating endothelial cells (By similarity). Tissue Location: Predominantly expressed in the peripheral nervous system and brain. Highest expression is observed in heart, lung, kidney, testis and moderate expression is present in spleen, pancreas, skeletal muscle, ovary and liver. Weakly expressed in glioblastoma (GBM) cell lines. Brain, Connective Tissue, Eye, Heart, Lung, Muscle, Skin tissues are correlated with this protein. Heart Diseases, Lung Diseases, Necrosis, Nervous System Diseases, Neurodegenerative Diseases are some of the diseases may be linked to PLEKHG5 Antibody (N-term) Blocking Peptide. The following patways have been known to be associated with this gene. PLEKHG5 also interacts with the following gene(s): CDC42, RAC1, RHOA.