PF 429242 inhibitor product blog
Tags: Inhibitor; PF 429242; PF 429242 inhibitor;
The PF 429242 n/a (Catalog #MBS5750106) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the PF 429242 with the following immunoassay(s):
Structure
CAS: 947303-87-9
Formula: C25H35N3O2.2HCl
Pathways: Membrane transporter/Ion channel
Target: SREBP1
Smiles: Cl.Cl.CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccccc1OC)[C@@H]1CCNC1. Receptor: SREBP1
Bioactivity: PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 muM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 muM).
Solubility Note: For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.