Pdgfd blocking peptide product blog
Tags: Blocking Peptide; PDGFD; SCDGFB; Pdgfd blocking peptide;
The Pdgfd pdgfd (Catalog #MBS9225995) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The Pdgfd pdgfd product has the following accession number(s) (GI #81868232) (NCBI Accession #Q9EQT1.1) (Uniprot Accession #Q9EQT1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (By similarity). May play an important role in control of lens epithelial cell proliferation. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
Cellular Location: Secreted. Note: Released by platelets upon wounding. Tissue Location: Widely expressed. Expressed at high levels in the kidney, adrenal glands, eye and CNS. In the kidney the localization is confined to arterial and arteriolar vascular smooth muscle cells and is also detected at low levels in the glomeruli In the eye in the anterior segment it is localized to the iris and ciliary body. In the retina localizes intensely to the outer plexiform layer, which contains photoreceptor axons and the synaptic layer between photoreceptors and second order neurons. In the spinal cord, prominently expressed in the motorneurons. Adenocarcinoma, Atherosclerosis, Cell Transformation, Neoplastic, Disease Models, Animal, Fibrosis, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Nervous System Diseases are some of the diseases may be linked to SCDGFB Antibody (Center) Blocking Peptide. The following patways have been known to be associated with this gene.