PDE8A blocking peptide product blog
Tags: Blocking Peptide; PDE8A; PDE8A blocking peptide;
The PDE8A pde8a (Catalog #MBS544233) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PDE8A can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition.Confocal Microscopy: 1:250
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Western Blot: 1:500-1:2,000. Researchers should empirically determine the suitability of the PDE8A pde8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE8A pde8a product has the following accession number(s) (GI #74727873) (NCBI Accession #Q86XV4) (Uniprot Accession #Q86XV4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide Pan Phosphodiesterase 8A N-epitope
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
Immunogen: Synthetic cyclic peptide from near the N terminus common to all PDE8A variants.
Expression: Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon. Determinant: N-epitope
Molecular Function: 3\', 5\'-cyclic-AMP phosphodiesterase activity, Hydrolase, Metal-binding
Structure: Belongs to cyclic nucleotide phosphodiesterase family. PDE8B subfamily. Contains 1 PAC (Pas-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain.
Subcellular Location: Cytosol. PDE8A also interacts with the following gene(s): ADCY10, ADCY3, ADCY7, ADCY9. Adrenal Gland, Blood, Brain, Eye, Heart, Muscle, Ovary, Pancreas, Spleen, Testis tissues are correlated with this protein.