|The PDE4A1 pde4a (Catalog #MBS544191) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PDE4A1 can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition.
Confocal Microscopy: 1:250
Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE4A1 pde4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE4A1 pde4a product has the following accession number(s) (GI #436013) (NCBI Accession #L27062.1) (Uniprot Accession #P54748). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Immunogen: Synthetic peptide specific for PDE4A1 protein.
Expression: Isoform 2 is testis specific. Molecular Function: Hydrolase, 3\', 5\'-cyclic-AMP phosphodiesterase activity, cAMP binding
Structure: Interacts with LYN and ARRB2.
Subcellular Location: Cytoplasm ; perinuclear region. PDE4A1 also interacts with the following gene(s): Adcy3, Adcy7. Brain, Embryonic Tissue, Kidney, Pancreas, Placenta, Testis, Uncharacterized Tissue tissues are correlated with this protein. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Cognition Disorders, Disease Models, Animal, Fibrosis, Heart Diseases, Hypertension, Inflammation, Learning Disorders, Memory Disorders, Necrosis are some of the diseases may be linked to PDE4A1 Peptide.