PDE11A3 positive control product blog
Tags: PDE11A3; Positive Control; PDE11A3 positive control;
The PDE11A3 pde11a (Catalog #MBS543058) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PDE11A3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE11A3 pde11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE11A3 pde11a product has the following accession number(s) (GI #10716053) (NCBI Accession #AB038041.1) (Uniprot Accession #Q9HCR9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Western Blot Positive Control Phosphodiesterase 11A3 Antibody
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5\'-AMP and 5\'-GMP, respectively.
Immunogen: Purified Protein
Expression: Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil� is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed. Molecular Function: Hydrolase, metal-ion binding, cGMP binding
Subcellular Location: Cytoplasm. The following patways have been known to be associated with this gene. Brain, Muscle, Nerve, Prostate, Testis tissues are correlated with this protein. Abnormalities, Multiple, Adenocarcinoma, Congenital Abnormalities, Disease Models, Animal, Heart Diseases, Hyperplasia, Hypertension, Infertility, Male, Memory Disorders, Precancerous Conditions are some of the diseases may be linked to PDE11A3 Antibody Western Blot Positive Control.