PARK2 positive control product blog
Tags: PARKIN; PARK2; Positive Control; PARK2 positive control;
The PARK2 park2 (Catalog #MBS543042) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Parkin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western Blot: 1:500. Researchers should empirically determine the suitability of the PARK2 park2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PARK2 park2 product has the following accession number(s) (GI #3063388) (NCBI Accession #BAA25751.1) (Uniprot Accession #O60260). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Acts within a multiprotein E3 ubiquitin ligase complex, by catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.� It also participates in the removal and/or detoxification of proteins that are abnormally folded or damaged.
Immunogen: Purified Protein
Expression: Expressed highly in the brain, and is also expressed in the heart, testis and skeletal muscle.� Expression is down-regulated or absent in tumor biopsies and in the brain of PARK2 patients. Molecular Function: Ligase, Chaperone binding, Protein kinase binding
Structure: Forms E3 ubiquitin ligase complex with UBE2L3 or UBE2L6.� Binds to C2A and C2B domains of SYTqq and interacts and regulates the turnovers of SEPT5.
Subcellular Location: Cytoplasm, Nucleus, Endoplasmic Reticulum, Mitochondrion. PARK2 also interacts with the following gene(s): GPR37, PINK1, PSMD4, SNCAIP, UBC, UBE2G1, UBE2L3, UBE2N. Brain Diseases, Cardiovascular Diseases, Cognition Disorders, Disease Models, Animal, Movement Disorders, Nervous System Diseases, Neurotoxicity Syndromes, Parkinson Disease, Parkinson Disease, Secondary, Parkinsonian Disorders are some of the diseases may be linked to Parkin Antibody Western Blot Positive Control. The following patways have been known to be associated with this gene. Adrenal Gland, Brain, Connective Tissue, Eye, Kidney, Mouth, Placenta, Prostate, Stomach, Testis tissues are correlated with this protein.