OxiSelect Comet Assay Slides (3-Well) assistant reagent product blog
Tags: Assistant Reagent; OxiSelect Comet Assay Slides (3-Well); OxiSelect Comet Assay Slides (3-Well) assistant reagent;
The OxiSelect Comet Assay Slides (3-Well) n/a (Catalog #MBS168261) is an Accessory Reagent and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given accessory reagent. We\'ve tested the OxiSelect Comet Assay Slides (3-Well) with the following immunoassay(s):
Testing Data
Background: DNA damage, due to environmental factors and normal metabolic processes inside the cell, occurs at a rate of 1,000 to 1,000,000 molecular lesions per cell per day. While this counts for only a small part of the human genome\'s approximately 6 billion bases (3 billion base pairs), unrepaired lesions to critical genes can impede a cell\'s ability to carry out its function and appreciably increase the likelihood of cancer. The comet assay, or single cell gel electrophoresis assay (SCGE), is a common technique for measurement of DNA damage in individual cells. Under an electrophoretic field, damaged cellular DNA (containing fragments and strand breaks) is separated from intact DNA, yielding a classic "comet tail" shape under the microscope. Extent of DNA damage is usually visually estimated by comet tail measurement; however, image analysis software is also available for measuring various parameters.