|The OSM osm (Catalog #MBS9220859) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The OSM osm product has the following accession number(s) (GI #129168) (NCBI Accession #P13725.2) (Uniprot Accession #P13725). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
Cellular Location: Secreted. The following patways have been known to be associated with this gene. OSM also interacts with the following gene(s): CNTF, CTF1, EPOR, IL11, IL6, IL6ST, JAK2, LIFR, OSMR, STAT3. Blood, Intestine, Kidney, Lung, Ovary, Thymus, Uncharacterized Tissue tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Hepatocellular, Disease Models, Animal, Fibrosis, Inflammation, Kidney Diseases, Liver Neoplasms, Lung Diseases, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to OSM Antibody (C-term) Blocking Peptide.