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NVP-ADW742 kinase inhibitor product blog

Posted on 2017-03-03 22:57:34 by mybiosource_staff
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Tags: Kinase Inhibitor; NVP-ADW742; NVP-ADW742 kinase inhibitor;
The NVP-ADW742 n/a (Catalog #MBS8506363) is a Kinase Inhibitor and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given kinase inhibitor. We\'ve tested the NVP-ADW742 with the following immunoassay(s):
Testing Data
Testing Data NVP-ADW742.

Biological Activity: NVP-ADW742 is an ATP-competitive inhibitor that inhibits IGF-1R autophosphorylation with a cellular IC50 of 0.1 to 0.2 umol/L, which is 16-fold lower than that of the insulin receptor[1]. NVP-ADW742 also enhances the sensitivity of SCLC to etoposide and carboplatin, which are commonly used in the treatment of SCLC[2].
Solubility: DMSO >=14mg/mL. Cas Number: 475488-23-4
Additional Specifications: NVP-ADW742 is an IGF-1R inhibitor with an IC50 of 0.1 to 0.2 uM. Target Product: IGF-1R.
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