NSUN2 blocking peptide product blog
Tags: Blocking Peptide; NSUN2; NSUN2 blocking peptide;
The NSUN2 nsun2 (Catalog #MBS9217896) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The NSUN2 nsun2 product has the following accession number(s) (GI #148887180) (NCBI Accession #Q08J23.2) (Uniprot Accession #Q08J23). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Cellular Location: Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Note: Concentrated in the nucleolus during interphase and translocates to the spindle during mitosis as an RNA-protein complex that includes 18S ribosomal RNA. Tissue Location: Expressed in adult and fetal brain and in lymphoblastoid cells. Brain, Embryonic Tissue, Heart, Liver, Pancreas, Prostate, Skin, Testis, Thyroid, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Cell Transformation, Neoplastic, Disease Models, Animal, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasm Metastasis, Neurobehavioral Manifestations, Skin Neoplasms are some of the diseases may be linked to NSUN2 Antibody (Center) Blocking peptide.