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NPHS1 blocking peptide product blog

Posted on 2015-10-18 10:08:57 by mybiosource_staff
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Tags: Nephrin; NPHS1; Blocking Peptide; NPHS1 blocking peptide;
The NPHS1 nphs1 (Catalog #MBS151783) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Nephrin can be used in a range of immunoassay formats including, but not limited to, Blocking (BL).
Nephrin peptide is used for blocking the activity of Nephrin antibody. Researchers should empirically determine the suitability of the NPHS1 nphs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NPHS1 nphs1 product has the following accession number(s) (GI #4758822) (NCBI Accession #NP_004637) (Uniprot Accession #O60500). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given blocking peptide. We\'ve tested the Nephrin Peptide with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Nephrin in mouse kidney tissue lysate with Nephrin antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide (2265P).)
Western Blot (WB) NPHS1.

Species: Human
Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location: 14 amino acid peptide from near the carboxy terminus of human Nephrin. NPHS1 also interacts with the following gene(s): CD2AP, FYN, KIRREL, NPHS2, SRC, TJP1, TRPC6. The following patways have been known to be associated with this gene. Disease Models, Animal, Glomerulonephritis, Glomerulosclerosis, Focal Segmental, Hypertension, Kidney Diseases, Kidney Failure, Chronic, Nephrosis, Nephrotic Syndrome, Proteinuria, Renal Insufficiency are some of the diseases may be linked to Nephrin Peptide. Brain, Kidney, Pancreas, Testis, Thymus tissues are correlated with this protein.
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