|The NOTCH1 notch1 (Catalog #MBS8212478) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The NOTCH1 Blocking Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NOTCH1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Researchers should empirically determine the suitability of the NOTCH1 notch1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NOTCH1 notch1 product has the following accession number(s) (GI #148833508) (NCBI Accession #NP_060087.3) (Uniprot Accession #P46531). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The peptide is used to block Anti-NOTCH1 Antibody reactivity.
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Heart, Liver, Muscle, Thymus, Vascular tissues are correlated with this protein. Breast Neoplasms, Cell Transformation, Neoplastic, Congenital Abnormalities, Inflammation, Leukemia, T-Cell, Liver Diseases, Lymphoma, Neoplasm Metastasis, Nervous System Diseases, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma are some of the diseases may be linked to NOTCH1 Blocking Peptide. NOTCH1 also interacts with the following gene(s): ADAM17, DTX1, FBXW7, HEY1, HEY2, MAML1, NUMB, PSEN1, RBPJ. The following patways have been known to be associated with this gene.