NCOR1 blocking peptide product blog
Tags: Blocking Peptide; NCOR1; NCOR1 blocking peptide;
The NCOR1 ncor1 (Catalog #MBS9218231) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The NCOR1 ncor1 product has the following accession number(s) (GI #47117817) (NCBI Accession #O75376.2) (Uniprot Accession #O75376). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Cellular Location: Nucleus
Clone Names: 2110611
Peptide ID: 2110611. NCOR1 also interacts with the following gene(s): ESR1, HDAC3, HDAC9, PPARG, RARA, TBL1X, THRB. Blood, Bone, Brain, Embryonic Tissue, Kidney, Liver, Muscle, Pituitary Gland, Prostate, Thyroid tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Disease Models, Animal, Fatty Liver, Hyperplasia, Inflammation, Liver Diseases, Liver Neoplasms, Nervous System Diseases are some of the diseases may be linked to NCOR1 Antibody (N-term) Blocking Peptide. The following patways have been known to be associated with this gene.