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Mubritinib kinase inhibitor product blog

Posted on 2017-07-22 04:20:54 by mybiosource_staff
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Tags: Kinase Inhibitor; Mubritinib; Mubritinib kinase inhibitor;
The Mubritinib n/a (Catalog #MBS8506551) is a Kinase Inhibitor and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given kinase inhibitor. We\'ve tested the Mubritinib (TAK 165) with the following immunoassay(s):
Testing Data
Testing Data Mubritinib.

Mubritinib(TAK 165) is a potent EGFR and p34cdc2 inhibitor with IC50 of 6 nM and 0.2 uM, respectively. Mubritinib(TAK 165) also inhibits p33cdk2 and p33cdk5. Mubritinib(TAK 165) displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Mubritinib(TAK 165) exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo. [1][2].

Solubility: Unknown. Formula: C25H23F3N4O2
CAS Number: 366017-09-6.
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