MTUS1 blocking peptide product blog
Tags: Blocking Peptide; MTUS1; MTUS1 blocking peptide;
The MTUS1 mtus1 (Catalog #MBS9230604) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The MTUS1 mtus1 product has the following accession number(s) (GI #158706128) (NCBI Accession #Q9ULD2.2) (Uniprot Accession #Q9ULD2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
Cellular Location: Mitochondrion. Golgi apparatus. Cell membrane. Nucleus. Note: In neurons, translocates into the nucleus after treatment with angiotensin-II. Tissue Location: Ubiquitously expressed (at protein level). Highly expressed in brain. Down-regulated in ovarian carcinoma, pancreas carcinoma, colon carcinoma and head and neck squamous cell carcinoma (HNSCC). Isoform 1 is the major isoform in most peripheral tissues. Isoform 2 is abundant in most peripheral tissues. Isoform 3 is the major isoform in brain, female reproductive tissues, thyroid and heart. Within brain it is highly expressed in corpus callosum and pons. Isoform 6 is brain- specific, it is the major isoform in cerebellum and fetal brain. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Hyperplasia, Hypertension, Hypertrophy, Inflammation, Neoplasm Metastasis are some of the diseases may be linked to MTUS1 Blocking Peptide (C-Term). Bladder, Blood, Brain, Heart, Liver, Lung, Muscle, Prostate, Skin, Vascular tissues are correlated with this protein. MTUS1 also interacts with the following gene(s): AGTR2, SPON2, UBE2V2.