msCD40L recombinant protein product blog
Tags: Recombinant Protein; soluble CD40 Ligand/TRAP; msCD40L recombinant protein; msCD40L;
The msCD40L cd40lg (Catalog #MBS142348) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.The msCD40L cd40lg product has the following accession number(s) (GI #15011846) (NCBI Accession #NP_035746.2) (Uniprot Accession #P27548). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Ar g-Gly-Asp.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including soluble CD40 Ligand/TRAP are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized sCD40 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: The ED50 as determined by its ability to induce MIP-1 alpha & TNF-alpha from mouse splenocytes was found to be 0.1 ug/ml corresponding to a Specific Activity of 10,000,000IU/mg. Anemia, Autoimmune Diseases, Cardiovascular Diseases, Heart Diseases, Hyper-IgM Immunodeficiency Syndrome, Type 1, Inflammation, Myocardial Infarction, Myocardial Ischemia, Necrosis, Pneumonia are some of the diseases may be linked to Recombinant Mouse soluble CD40 Ligand/TRAP. The following patways have been known to be associated with this gene. msCD40L also interacts with the following gene(s): Cd40, Cd80, Cd86, Foxp3, Icam1, Il2, Tnfsf13b, Traf1.