Mogat2 blocking peptide product blog
Tags: Blocking Peptide; MOGAT2; MOGT2; Mogat2 blocking peptide;
The Mogat2 mogat2 (Catalog #MBS9218241) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The Mogat2 mogat2 product has the following accession number(s) (GI #81873317) (NCBI Accession #Q80W94.1) (Uniprot Accession #Q80W94). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.
Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Location: Mainly expressed in small intestine. Detected in the small intestine in a proximal-to-distal gradient that correlated with fat absorption pattern. Present not only in the villi, but also in the crypt regions of the small intestine, which suggests that expression occurs prior to the maturation of enterocytes. Not detectable in other sections of the digestive tract, including stomach, cecum, colon and rectum, or other tissues such as kidney, liver and adipocytes (at protein level) Also detected in kidney, adipose and stomach. Expressed at very low level in liver, skeletal muscle and spleen. Not expressed in brain, heart, lung, skin, testis and thymus. The following patways have been known to be associated with this gene. Breast Neoplasms, Cardiovascular Diseases, Fatty Liver, Liver Diseases, Non-alcoholic Fatty Liver Disease, Weight Gain, Weight Loss are some of the diseases may be linked to Mouse MOGT2 Antibody (C-term) Blocking Peptide. Intestine, Liver tissues are correlated with this protein.