MECP2 blocking peptide product blog
Tags: MECP2; Blocking Peptide; MeCP2 blocking peptide; MeCP2 (S421);
The MECP2 mecp2 (Catalog #MBS9224718) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The MECP2 mecp2 product has the following accession number(s) (GI #50401118) (NCBI Accession #Q95LG8.1) (Uniprot Accession #Q95LG8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).
Cellular Location: Nucleus. Note: Colocalized with methyl-CpG in the genome. Angelman Syndrome, Autistic Disorder, Child Development Disorders, Pervasive, Cognition Disorders, Developmental Disabilities, Intellectual Disability, Learning Disorders, Memory Disorders, Rett Syndrome, Seizures are some of the diseases may be linked to MeCP2 Antibody (S421) Blocking Peptide.