MBD3 blocking peptide product blog
Tags: Blocking Peptide; MBD3; MBD3 blocking peptide;
The MBD3 mbd3 (Catalog #MBS9217566) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The MBD3 mbd3 product has the following accession number(s) (GI #50400820) (NCBI Accession #O95983.1) (Uniprot Accession #O95983). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
Cellular Location: Nucleus. Chromosome. Note: Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Disease Models, Animal, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to MBD3 Antibody (C-term) Blocking Peptide. Blood, Brain, Embryonic Tissue, Eye, Liver, Lung, Muscle, Nerve, Skin, Testis tissues are correlated with this protein.