Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Blog  rightarrow Map2k4 blocking peptide  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • GSK3B sirna blog
 • Tos-Arg-OMe; HCl [TAME] enzyme substrate blog
 • anti-BMP4 antibody blog
 • PSMB4 sirna blog
 • PPP6R1 sirna blog
 • Amlexanox inhibitor blog
 • SORCS3 sirna blog
 • SH3GL3 sirna blog
 • Uric acid (BSA) conjugate antigen blog
 • Tie2 kinase inhibitor kinase inhibitor blog
 • WDR89 shrna blog
 • anti-PKM antibody blog
 • KRTAP9-3 sirna blog
 • anti-Clostridium Botullinum B Toxoid antibody blog
 • anti-CLEC2 antibody blog
 • anti-VSV-G HRP antibody blog
 • TCTP elisa kit blog
 • anti-Mmp-1 antibody blog
 • Dengue virus 2 recombinant protein blog
 • SF3B3 elisa kit blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • Interferon-induced protein with tetratricopeptide repeats 3,... ELISA Kit
 • ADP-ATP translocase 1 (SLC25A4) ELISA Kit
 • Glycogen ELISA Kit
 • Jumonji Domain Containing 2C (KDM4C) Antibody
 • a1-Microglobulin Antibody
 • Dickkopf-related protein 1 (DKK-1) ELISA Kit
 • Apoptosis Inducing Factor (AIF) ELISA Kit
 • U-box domain-containing protein 56 (PUB56) Recombinant Protein
 • Newcastle Disease Virus Antibody
 • Superoxide Dismutase-1 (SOD1) Recombinant Protein
 • FABP4 Antibody
 • Pentagastrin Peptide
 • Spastin (SPAST) ELISA Kit
 • Catenin Beta 1 (CTNNb1) Antibody
 downarrow more ...
separator

Map2k4 blocking peptide product blog

separator
Posted on 2018-02-13 02:21:05 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Blocking Peptide; Map2k4; MAP2K4 blocking peptide;
separator
The Map2k4 map2k4 (Catalog #MBS9221232) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.

The Map2k4 map2k4 product has the following accession number(s) (GI #2507202) (NCBI Accession #P47809.2) (Uniprot Accession #P47809). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of the Thr residue by MAP2K7/MKK7 seems to be the prerequisite for JNK activation at least in response to proinflammatory cytokines, while other stimuli activate both MAP2K4/MKK4 and MAP2K7/MKK7 which synergistically phosphorylate JNKs. MAP2K4 is required for maintaining peripheral lymphoid homeostasis. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Whereas MAP2K7/MKK7 exclusively activates JNKs, MAP2K4/MKK4 additionally activates the p38 MAPKs MAPK11, MAPK12, MAPK13 and MAPK14.

Map2k4 map2k4

Cellular Location: Cytoplasm. Nucleus. Tissue Location: Strong expression is detected in most of the central nervous system and in liver and thymus during early stages of development. While expression in nervous system increases over time, expression in fetal liver and thymus gradually decreases as embryogenesis proceeds. High level of expression in the central nervous system persists throughout postnatal development and remained at a stable level in adult brain. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Inflammation, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasms, Experimental, Pancreatic Neoplasms, Prostatic Neoplasms are some of the diseases may be linked to Mouse Map2k4 Antibody (C-term) Blocking Peptide. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Lymph Node, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions