|The MAP1LC3C map1lc3c (Catalog #MBS9223070) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The MAP1LC3C map1lc3c product has the following accession number(s) (GI #84028113) (NCBI Accession #Q9BXW4.1) (Uniprot Accession #Q9BXW4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.
Cellular Location: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3-II binds to the autophagic membranes. Tissue Location: Most abundant in placenta, lung and ovary. The following patways have been known to be associated with this gene. Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Leukemia, Leukemia, Myeloid, Acute, Lung Neoplasms, Melanoma are some of the diseases may be linked to LC3 Antibody (APG8c) (N-term) Blocking Peptide.