|The MAP1LC3A map1lc3a (Catalog #MBS9229299) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The MAP1LC3A map1lc3a product has the following accession number(s) (GI #85701362) (NCBI Accession #Q9H492.2) (Uniprot Accession #Q9H492). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Cellular Location: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3-II binds to the autophagic membranes. Tissue Location: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. The following patways have been known to be associated with this gene. Brain, Eye, Heart, Intestine, Kidney, Liver, Lung, Muscle, Nerve, Prostate tissues are correlated with this protein. Carcinoma, Hepatocellular, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Lung Diseases, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to MAP1LC3A Blocking Peptide (C-term).