LRP1 blocking peptide product blog
Tags: LRP1; Blocking Peptide; LRP1 blocking peptide; LPR1 (S4520);
The LRP1 lrp1 (Catalog #MBS9225029) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The LRP1 lrp1 product has the following accession number(s) (GI #317373384) (NCBI Accession #Q07954.2) (Uniprot Accession #Q07954). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.
Cellular Location: Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm. Nucleus. Note: After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus. Tissue Location: Most abundant in liver, brain and lung. LRP1 also interacts with the following gene(s): APOE, HSP90AA1, LPL, LRPAP1, PDGFRB, PLAT, SERPINE1, THBS1. Atherosclerosis, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Hypercholesterolemia, Inflammation, Liver Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Phospho-LPR1(S4520) Antibody Blocking peptide. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Connective Tissue, Embryonic Tissue, Heart, Liver, Muscle, Nerve, Vascular tissues are correlated with this protein.