LPL blocking peptide product blog
Tags: LPL; Blocking Peptide; LPL blocking peptide;
The LPL lpl (Catalog #MBS9220530) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The LPL lpl product has the following accession number(s) (GI #126314) (NCBI Accession #P06858.1) (Uniprot Accession #P06858). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity).
Cellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note: Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). Adipose Tissue, Blood, Bone, Connective Tissue, Heart, Intestine, Kidney, Liver, Muscle, Vascular tissues are correlated with this protein. Atherosclerosis, Cardiovascular Diseases, Dyslipidemias, Fatty Liver, Heart Diseases, Hyperlipidemias, Hypertriglyceridemia, Insulin Resistance, Necrosis, Obesity are some of the diseases may be linked to LPL Antibody (Center) Blocking Peptide. The following patways have been known to be associated with this gene. LPL also interacts with the following gene(s): APOA1, APOB, APOC2, APOC3, APOE, GPIHBP1, LMF1, LRP1, PPARA, PPARG.