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LGALS3 recombinant protein product blog

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Posted on 2014-07-30 17:00:56 by mybiosource_staff
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Tags: Galectin 3; LGALS3; Recombinant Protein; LGALS3 recombinant protein;
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The LGALS3 lgals3 (Catalog #MBS538161) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Galectin 3 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the LGALS3 lgals3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The LGALS3 lgals3 product has the following accession number(s) (GI #2385452) (NCBI Accession #BAA22164.1) (Uniprot Accession #P17931). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Region of Galectin 3 protein correspond ing to amino acids ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYHGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSAPGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Galectin 3 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.

LGALS3 lgals3

Protein Type: Recombinant
Biological Significance: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes.
Bioactivity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained at 250 ug/ml.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Thyroid, Vascular tissues are correlated with this protein. Adenocarcinoma, Adenoma, Breast Neoplasms, Carcinoma, Disease Models, Animal, Fibrosis, Heart Diseases, Inflammation, Lung Diseases, Neoplasm Metastasis are some of the diseases may be linked to Galectin 3 protein. LGALS3 also interacts with the following gene(s): DDOST, GEMIN4, HRAS, LGALS3BP, MMP2, NRAS, PRKCSH, PTPRC, SUFU, TNC.
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