|The LEC n/a (Catalog #MBS539381) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s LEC can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the LEC n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:
Region of LEC protein correspond ing to amino acids QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including LEC are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils.
Bioactivity: Determined by its ability to chemoattract total human monocytes using a concentration range of 10-100 ng/ml.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli.