The LAG-3:Fc n/a (Catalog #MBS637219) is an Active Protein produced from Recombinant human LAG-3 produced in CHO cells. and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The sequence coding for the 4 extracellu lar Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including LAG-3:Fc are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Biological Activity: Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells. Endotoxin(LAL): = or < 0.1EU/ug; < 0.1EU/ug.