|The KRT1 krt1 (Catalog #MBS9228346) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The KRT1 krt1 product has the following accession number(s) (GI #238054406) (NCBI Accession #P04264.6) (Uniprot Accession #P04264). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Cellular Location: Cell membrane. Note: Located on plasma membrane of neuroblastoma NMB7 cells. Tissue Location: The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. Bladder, Blood, Brain, Heart, Lung, Mammary Gland, Mouth, Skin, Thymus, Uterus tissues are correlated with this protein. Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Hyperkeratosis, Epidermolytic, Hyperplasia, Immune System Diseases, Inflammation, Keratoderma, Palmoplantar, Epidermolytic, Lung Diseases, Necrosis, Skin Neoplasms are some of the diseases may be linked to KRT1 Antibody (Center) Blocking Peptide. KRT1 also interacts with the following gene(s): CTNNB1, IVL, KRT10, KRT2, LEF1, LOR, UBC. The following patways have been known to be associated with this gene.