|The KRAS kras (Catalog #MBS9221352) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The KRAS kras product has the following accession number(s) (GI #131875) (NCBI Accession #P01116.1) (Uniprot Accession #P01116). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838).
Cellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. KRAS also interacts with the following gene(s): ARAF, BCL2, EGFR, MAP2K1, PIK3CA, PTPN11, RAF1, RALGDS, SOS1, TP53. The following patways have been known to be associated with this gene. Adenocarcinoma, Carcinogenesis, Carcinoma, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Disease Models, Animal, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental, Pancreatic Neoplasms are some of the diseases may be linked to KRAS2 Antibody (C-term) Blocking Peptide. Blood, Bone, Brain, Liver, Lung, Lymph, Lymph Node, Pancreas, Skin, Vascular tissues are correlated with this protein.