KMO blocking peptide product blog
Tags: Blocking Peptide; KMO; KMO blocking peptide;
The KMO kmo (Catalog #MBS9227774) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The KMO kmo product has the following accession number(s) (GI #126302562) (NCBI Accession #O15229.2) (Uniprot Accession #O15229). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Cellular Location: Mitochondrion outer membrane; Multi-pass membrane protein. Tissue Location: Highest levels in placenta and liver. Detectable in kidney. The following patways have been known to be associated with this gene. Brain, Kidney, Mixed tissues are correlated with this protein. Anemia, Carcinoma, Cardiovascular Diseases, Cognition Disorders, Inflammation, Liver Diseases, Liver Neoplasms, Memory Disorders, Necrosis, Poisoning are some of the diseases may be linked to KMO Antibody (Center) Blocking Peptide.