KLF4 blocking peptide product blog
Tags: KLF4; Blocking Peptide; KLF4 blocking peptide;
The KLF4 klf4 (Catalog #MBS9229668) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The KLF4 klf4 product has the following accession number(s) (GI #223590252) (NCBI Accession #O43474.3) (Uniprot Accession #O43474). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Transcription factor; can act both as activator and as repressor. Binds the 5\'-CACCC-3\' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
Cellular Location: Nucleus. The following patways have been known to be associated with this gene. Breast Neoplasms, Carcinoma, Squamous Cell, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Inflammation, Liver Neoplasms, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to KLF4 Blocking Peptide (C-term). Brain, Embryonic Tissue, Eye, Heart, Intestine, Kidney, Liver, Lung, Skin, Vascular tissues are correlated with this protein.