|The KLF11 klf11 (Catalog #MBS9226207) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The KLF11 klf11 product has the following accession number(s) (GI #11387048) (NCBI Accession #O14901.2) (Uniprot Accession #O14901). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Transcription factor. Activates the epsilon- and gamma- globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.
Cellular Location: Nucleus. Tissue Location: Ubiquitous. Higher expression in erythroid cells. KLF11 also interacts with the following gene(s): EP300, GAPDH, SIN3A, SMAD3, SMAD7, STAT3. The following patways have been known to be associated with this gene. Cell Transformation, Neoplastic, Depressive Disorder, Disease Models, Animal, Drug-Related Side Effects and Adverse Reactions, Fatty Liver, Fibrosis, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis are some of the diseases may be linked to TIEG2 Antibody (N-term) Blocking Peptide. Blood, Bone, Brain, Heart, Liver, Lung, Muscle, Pancreas, Uterus, Vascular tissues are correlated with this protein.