JAG1 blocking peptide product blog
Tags: Blocking Peptide; JAG1; JAG1 blocking peptide;
The JAG1 jag1 (Catalog #MBS9230135) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The JAG1 jag1 product has the following accession number(s) (GI #20455033) (NCBI Accession #P78504.3) (Uniprot Accession #P78504). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Cellular Location: Membrane; Single-pass type I membrane protein. Tissue Location: Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells. The following patways have been known to be associated with this gene. Alagille Syndrome, Bone Diseases, Brain Diseases, Breast Neoplasms, Chromosome Aberrations, Facies, Heart Defects, Congenital, Heart Diseases, Liver Diseases, Tetralogy of Fallot are some of the diseases may be linked to JAG1 Blocking Peptide (C-term). Blood, Brain, Connective Tissue, Embryonic Tissue, Intestine, Kidney, Lung, Pancreas, Placenta, Prostate tissues are correlated with this protein.