IL33 recombinant protein product blog
Tags: Recombinant Protein; IL33; Interleukin-33 (Western Blot Control); IL33 recombinant protein;
The IL-33 il33 (Catalog #MBS343181) is a Western Blot Control and is intended for research purposes only. The product is available for immediate purchase.The IL-33 il33 product has the following accession number(s) (GI #15559209) (NCBI Accession #NP_254274.1) (Uniprot Accession #O95760). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Interleukin 33 (IL-33) is a proimflammatory cytokine belonging to the IL-1 family. IL-33 is cleaved in vivo, generating an N terminal and a C terminal fragment. The C terminal fragment corresponds to the mature IL-33 protein and mediates its biological effect by interacting with the IL-1 receptor, also known as ST2. Binding of mature IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces the production of associated cytokines in particular IL-4, IL-5 and IL-13 causing severe pathological changes in mucosal organs. Recombinant Interleukin-33 comprises a 159 amino acid fragment (112-270) corresponding to C terminal Interleukin-33 fragment coding sequence and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
Buffer: Buffered 50% glycerol. Asthma, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hypersensitivity, Immediate, Inflammation, Lung Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Interleukin-33 (IL-33) (Western Blot Control). IL-33 also interacts with the following gene(s): CASP1, CD69, IL1RL1, IL6, ITGAM, KIT, TFF2, TNFSF11, VEGFA. Adipose Tissue, Brain, Connective Tissue, Heart, Intestine, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.