IL15RA blocking peptide product blog
Tags: Blocking Peptide; IL15RA; IL15RA blocking peptide;
The IL15RA il15ra (Catalog #MBS9223785) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The IL15RA il15ra product has the following accession number(s) (GI #59799763) (NCBI Accession #Q13261.1) (Uniprot Accession #Q13261). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK.
Cellular Location: Membrane; Single-pass type I membrane protein Nucleus membrane; Single-pass type I membrane protein. Note: Mainly found associated with the nuclear membrane Isoform 6: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note: Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, Golgi and cytoplasmic vesicles, but not with the nuclear membrane Isoform 8: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note: Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, Golgi and cytoplasmic vesicles, but not with the nuclear membrane. Tissue Location: Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures. Blood, Brain, Eye, Intestine, Liver, Lung, Prostate, Skin, Spleen, Uterus tissues are correlated with this protein. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Disease Models, Animal, Inflammation, Liver Diseases, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasms, Experimental, Nervous System Diseases, Vascular Diseases are some of the diseases may be linked to IL15RA Antibody (Center) Blocking Peptide.