IL 7 recombinant protein product blog
Tags: Recombinant Protein; Interleukin-7; IL 7 recombinant protein; IL 7;
The IL 7 il7 (Catalog #MBS142131) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.The IL 7 il7 product has the following accession number(s) (GI #4504677) (NCBI Accession #NP_000871.1) (Uniprot Accession #P13232). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
DCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Interleukin-7 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized Interleukin -7 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Protein Content: Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.418 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a standard solution of IL-7 as a Reference Standard.
Biological Activity: The ED50 as determined by the dose-dependant stimulation of murine IXN/2B cells is < 0.5ng/ml, corresponding to a Specific Activity of 2,000,000 IU/mg. Carcinoma, Cell Transformation, Neoplastic, Death, Hypersensitivity, Inflammation, Lymphopenia, Multiple Sclerosis, Necrosis, Neoplasms, Experimental, Sepsis are some of the diseases may be linked to Recombinant Human Interleukin-7. Blood, Bone, Brain, Intestine, Kidney, Liver, Lymph Node, Skin, Spleen, Thymus tissues are correlated with this protein. IL 7 also interacts with the following gene(s): CSF2, FOXP3, IL2RA, IL2RG, IL3, IL7R, IL9, JAK1, JAK3. The following patways have been known to be associated with this gene.