|The IL 4 il4 (Catalog #MBS142359) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The IL 4 il4 product has the following accession number(s) (GI #4504669) (NCBI Accession #NP_000580.1) (Uniprot Accession #P05112). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MGSSHHH HHH SSGLVPRGSH MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Interleukin-4 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Biological Activity: The ED50 for this effect is <1.8ng/ml. Measured in a cell proliferation assay using TF1 human erythroleukemic cells. Blood, Spleen tissues are correlated with this protein. IL 4 also interacts with the following gene(s): CSF2, FOS, IL13RA1, IL2RG, IL4R, IL5, JAK2, STAT6. Asthma, Autoimmune Diseases, Hypersensitivity, Hypersensitivity, Immediate, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Respiratory Hypersensitivity, Rhinitis are some of the diseases may be linked to Recombinant Human Interleukin-4, His Tag. The following patways have been known to be associated with this gene.