IL-17 recombinant protein product blog
Tags: Recombinant Protein; Interleukin-17A; IL-17; IL-17 recombinant protein;
The IL-17 il17a (Catalog #MBS553185) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.The IL-17 il17a product has the following accession number(s) (GI #4504651) (NCBI Accession #NP_002181.1) (Uniprot Accession #Q16552). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MRMLLHLSLL ALGAAYVYAI PTEIPTSALV KETLALLSTH RTLLIANETL RIPVPVHKNH QLCTEEIFQG IGTLESQTVQ GGTVERLFKN LSLIKKYIDG QKKKCGEERR RVNQFLDYLQ EFLGVMNTEW IIES.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Interleukin-17A are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Domain: four helix cytokine core
Host Note: Optimized DNA sequence encoding Human Interleukin-17A mature chain was expressed in Escherichia Coli. Endotoxin: Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Molecular Weight Note: Native human Interleukin17A, generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculated molecular mass of approximately 16kDa.
Recombinant IL-17A is a disulfide-linked homodimeric protein consisting of two 137 amino acid residue subunits, and migrates as an approximately 31kDa protein under non-reducing conditions and as a 16 kDa protein under reducing conditions in SDS-PAGE. Arthritis, Experimental, Asthma, Eye Diseases, Fibrosis, Hypersensitivity, Inflammation, Liver Diseases, Neoplasms, Respiratory Hypersensitivity, Respiratory Tract Diseases are some of the diseases may be linked to Human Interleukin-17A Recombinant. IL-17 also interacts with the following gene(s): IL17RA. Mixed tissues are correlated with this protein. The following patways have been known to be associated with this gene.