IgG immunoglobulin product blog
Tags: IgG; Immunoglobulin; IgG immunoglobulin; Mouse IgG (Fc);
The IgG n/a (Catalog #MBS537224) is an Immunoglobulin produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Mouse IgG (Fc) can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the IgG n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given immunoglobulin. We\'ve tested the Mouse IgG (Fc) with the following immunoassay(s):
SDS-PAGE (Lane 1: 5 uL MW Marker. Lane 2: Reduced Mouse IgG Whole Molecule. Lane 3: Reduced Mouse F(c) Fragment. Lane 4: Reduced Mouse F(ab) Fragment. Lane 5: Mouse IgM Kappa Myeloma Protein. Load: 1 ug per lane. Predicted/Observed size: IgG at 50 and 25 kDa; F(c) at 25 kDa; F(ab) at 25 kDa; IgM K at 70 and 23 kDa. Observed F(c) Fragment migrates slightly higher.)
Purified Mouse IgG (Fc).
Grade: Highly Purified
Source: Mouse Serum delipidated, fractionated, ion-exchange chromatography & papain difestion. Biohazard Information: Use Normal Laboratory Techniques when handling this material
Biological Significance: Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains - two heavy chains and two light chains. Each IgG has two antigen binding sites. Other Immunoglobulins may be described in terms of polymers with the IgG structure considered the monomer. The Fc regions of IgGs bear a highly conserved N-glycosylation site. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6-linked sialic acid residues.