|The HSD11B2 hsd11b2 (Catalog #MBS9228387) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The HSD11B2 hsd11b2 product has the following accession number(s) (GI #30316367) (NCBI Accession #P80365.2) (Uniprot Accession #P80365). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Cellular Location: Microsome. Endoplasmic reticulum. Tissue Location: Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon. The following patways have been known to be associated with this gene. Brain, Connective Tissue, Heart, Intestine, Kidney, Liver, Lung, Placenta, Testis, Uterus tissues are correlated with this protein. Apparent mineralocorticoid excess, Cardiovascular Diseases, Hyperplasia, Hypertension, Inflammation, Kidney Diseases, Mineralocorticoid Excess Syndrome, Apparent, Necrosis, Pregnancy Complications, Renal Insufficiency are some of the diseases may be linked to HSD11B2 Antibody (Center) Blocking Peptide.